BONE CHANGES IN LEPROSY: pathogenesis, palaeopathological diagnostic criteria, and clinical interpretation
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[Application of the diagnostic criteria for systemic lupus erythematosus to patients with multibacillary leprosy].
INTRODUCTION Systemic lupus erythematosus (SLE) is a chronic inflammatory disease that affects multiple organs or systems. There is no pathognomonic clinical or laboratory test sensitive and specific enough for a specific diagnosis. The criteria proposed by the American College of Rheumatology (ACR), as modified in 1997, are used for the diagnosis. The presence of four or more criteria presents...
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متن کامل"Tap sign" in tuberculoid and borderline tuberculoid leprosy.
Deep pain upon percussion of lesions over bone in tuberculoid leprosy, in spite of superficial sensory impairment, has been described as the "Tap Sign" (TS). This study was conducted to identify possible causes for this phenomenon and to determine the sensitivity and specificity of this sign in leprosy patients with lesions overlying bone. In 37/53 patients with lesions over bone, the sensitivi...
متن کاملStudy of Multiple Myeloma Occurrence in Patients With 5%-10% Bone Marrow Plasma Cells: A Case Series Regarding Revised IMWG Diagnostic Criteria
Introduction: Utilizing lower limit of bone marrow plasma cells (BMPCs) is the main existing criterion for diagnosis of multiple myeloma (MM). According to the revised international myeloma working group (IMWG) diagnostic criteria, the value of 10% is agreed among experts as the cutoff level for diagnosis. Symptomatic patients with BMPC above this value are identified as definite cases of MM. H...
متن کاملThe role of nerve biopsies in the diagnosis and management of leprosy.
Skin and nerve biopsies from 81 patients clinically suspected to have leprosy were studied. Histologically 54% of the patients showed leprosy. Both nerve and skin biopsies were histologically diagnostic of leprosy in 64% of these cases while 32% were diagnostic in the nerve but not skin biopsy. In the 11 patients with multibacillary leprosy (BI greater than or equal to 2) a multibacillary pictu...
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